Category Archives: Migraine

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What is gabapentin?

Gabapentin is an anti-epileptic medication, also called an anticonvulsant. It affects chemicals and nerves in the body that are involved in the cause of seizures and some types of pain.  Gabapentin is used in adults to treat nerve pain caused by herpes virus or shingles (herpes zoster).

The Horizant brand of gabapentin is also used to treat restless legs syndrome (RLS). The Neurontin brand of gabapentin is also used to treat seizures in adults and children who are at least 3 years old.  Gabapentin is also used to cure migraine. Gabapentin is effective in insomnia. Gabapentin is effective in alleviating itching in renal failure (uremic pruritus) and itching of other etiologies.

Use only the brand and form of gabapentin that your doctor has prescribed. Check your medicine each time you get a refill at the pharmacy, to make sure you have received the correct form of this medication.

Gabapentin was first approved for use in 1993. In the United States it has been available as a generic medication since 2004.

Gabapentin may be useful in the treatment of comorbid anxiety in bipolar patients, (however not the bipolar state itself).  Gabapentin may be effective in acquired pendular nystagmus and infantile nystagmus, (but not periodic alternating nystagmus). It is effective in hot flashes. It may be effective in reducing pain and spasticity in multiple sclerosis. Gabapentin may reduce symptoms of alcohol withdrawal (but it does not prevent the associated seizures). Use for smoking cessationhas had mixed results.


In 2009 the U.S. Food and Drug Administration issued a warning of an increased risk of depression and suicidal thoughts and behaviors in patients taking gabapentin, along with other anticonvulsant drugs.  modifying the packaging insert to reflect this.  A 2010 meta analysis confirmed the increased risk of suicide associated with gabapentin use.

Gabapentin Mechanism of action

The mechanism of the anticonvulsant action of gabapentin has not been fully described. Though similar in structure to the endogenous neurotransmitter GABA, gabapentin has not been shown to bind to GABA receptors at concentrations at or below 1 mM.  Gabapentin modulates the action of glutamate decarboxylase (GAD) and branched chain aminotransferase (BCAT), two enzymes involved in GABA biosynthesis. In human and rat studies, gabapentin was found to increase GABA biosynthesis, and to increase non-synaptic GABA neurotransmission in vitro.


Gabapentin has been shown to bind to the α2δ-1 subunit of voltage gated calcium ion channels which attributes to its pain attenuation effects in diabetic neuropathy and post-herpetic neuralgia. Other neurophysiological findings indicate that gabapentin also interacts with NMDA receptors, protein kinase C, and inflammatory cytokines

HOW TO USE Gabapentin

Neurontin 800 mgRead the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking gabapentin and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor. Dosage is based on your medical condition and response to treatment. For children, the dosage is also based on weight.

If you are taking the tablets and your doctor directs you to split the tablet in half, take the other half-tablet at your next scheduled dose. Discard half tablets if not used within several days of splitting them. If you are taking the capsules, swallow them whole with plenty of water.

It is very important to follow your doctor’s dosing instructions exactly. During the first few days of treatment, your doctor may gradually increase your dose so your body can adjust to the medication. To minimize side effects, take the very first dose at bedtime.

Take this medication regularly to get the most benefit from it. This drug works best when the amount of medicine in your body is kept at a constant level. Therefore, take gabapentin at evenly spaced intervals at the same time(s) each day. If you are taking this medication 3 times a day to control seizures, do not let more than 12 hours pass between doses because your seizures may increase.

Do not take this medication more often or increase your dose without consulting your doctor. Your condition will not improve any faster and the risk of serious side effects may increase.

Do not stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased.

Antacids containing aluminum or magnesium may interfere with the absorption of this medication. Therefore, if you are also taking an antacid, it is best to take gabapentin at least 2 hours after taking the antacid.

Different forms of gabapentin (such as immediate-release, sustained-release, enacarbil sustained-release) are absorbed in the body differently. Do not switch from one form to the other without consulting your doctor.

Tell your doctor if your condition does not improve or if it worsens.

What Diseases can Gabapentin be treated ?

By, Gabapentin Can be used for a lot of Nerve Pain related health conditions.
including Cough, Hot Flashes, Alcohol Withdrawal, Anxiety 161 reviews, Bipolar Disorder, Trigeminal Neuralgia, Postherpetic Neuralgia, Migraine, Insomnia, Occipital Neuralgia, Peripheral Neuropathy,Vulvodynia, Benign Essential Tremor, Epilepsy, Fibromyalgia, Pain Relief, Diabetic Peripheral Neuropathy , Neuropathic Pain,Reflex Sympathetic Dystrophy Syndrome,Periodic Limb Movement Disorder, Spondylolisthesis, Burning Mouth Syndrome,Pudendal Neuralgia, Small Fiber Neuropathy.

A lot of Patients use Gabapentin (Neurontin) to treat Hot Flashes, Anxiety, Bipolar Disorder, Migraine, Insomnia, Restless Legs Syndrome, Peripheral Neuropathy, Fibromyalgia, Neuropathic Pain. Fe patients use gabapentin to treat Pruritus, Cough, Occipital Neuralgia, Benign Essential Tremor, ement Disorder, Spondylolisthesis, Burning Mouth Syndrome, Pudendal Neuralgia, Small Fiber Neuropathy.

What you must know before you take Gabapentin 

Before taking gabapentin, tell your doctor or pharmacist if you are allergic to it; or to gabapentin enacarbil; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, mental/mood problems (such as depression, thoughts of suicide), use/abuse of drugs/alcohol.

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the side effects of this drug, especially swelling of the hands/ankles/feet, dizziness, or loss of coordination. Dizziness and loss of coordination can increase the risk of falling.

Children may be more sensitive to the side effects of this drug, especially mental/mood/behavior changes (such as hostility, problems concentrating, restlessness).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

Gabapentin passes into breast milk. Consult your doctor before breast-feeding.

Butalbital Abuse and Dependence

Barbiturates may be habit-forming: Tolerance, psychological dependence, and physical dependence may occur especially following prolonged use of high doses of barbiturates. The average daily dose for the barbiturate addict is usually about 1500 mg. As tolerance to barbiturates develops, the amount needed to maintain the same level of intoxication increases; tolerance to a fatal dosage, however, does not increase more than two-fold.


As this occurs, the margin between an intoxication dosage and fatal dosage becomes smaller. The lethal dose of a barbiturate is far less if alcohol is also ingested. Major withdrawal symptoms (convulsions and delirium) may occur within 16 hours and last up to 5 days after abrupt cessation of these drugs. Intensity of withdrawal symptoms gradually declines over a period of approximately 15 days. Treatment of barbiturate dependence consists of cautious and gradual withdrawal of the drug.


Barbiturate-dependent patients can be withdrawn by using a number of different withdrawal regimens. One method involves initiating treatment at the patient’s regular dosage level and gradually decreasing the daily dosage as tolerated by the patient. has very detail on what you should know when you order fioricet online, please check the website yourself

What is fioricet ?

Fioricet contains a combination of acetaminophen, butalbital, and caffeine. Acetaminophen is a pain reliever and fever reducer. Butalbital is in a group of drugs called barbiturates. It relaxes muscle contractions involved in a tension headache. Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow.

Fioricet is used to treat tension headaches that are caused by muscle contractions.

Each tablet contains the following active ingredients:
butalbital USP . . . . . . . . . . . .50 mg
acetaminophen USP . . . . . . 325 mg
caffeine USP . . . . . . . . . . . . .40 mg

Inactive Ingredients: crospovidone, FD&C Blue #1, magnesium stearate, microcrystalline cellulose, povidone, pregelatinized starch, and stearic acid.


Migraine Surgery

If you suffer from debilitating migraines, then you know how painful and limiting the neurological disorder can be. You’ve been forced to miss important events due to that pulsating pain and ever-present nausea. You’ve even had to adjust to lifestyle changes, making sure you get just enough sleep—not too little and not too much. You take the medicines regularly, both the preventative type and the kind that helps you deal with an attack. Yet you still don’t have a good handle on your disorder—the treatments aren’t helping as much as you need them too, and you’re rapidly losing the small amount of control you have. If this sounds like you, it might be a good idea to do some research about new migraine surgeries.

What Happens

In 2003 and 2004, surprisingly positive side effects were discovered to a plastic surgery procedure, the forehead rejuvenation. Patients who’d had the operation, which includes cutting into muscle, reported that their migraines disappeared. Based on that finding, some medical professionals designed two surgical techniques that identify migraine trigger points and treat the headaches. Another type of migraine surgery involves cauterization of superficial blood vessels located in the scalp. Finally, one last type of procedure deals with the correction of a congenital heart defect.


Surgery is a good option for several types of patients. Those individuals who don’t respond well to medication, who encounter nasty side effects from their pills, or who prefer to not be on medication permanently are great candidates for surgery. Furthermore, one small study shows that over ninety percent of migraine sufferers who went under the knife saw a fifty percent reduction in their headaches, via intensity, duration, or occurrence. Thirty-five percent of that group reported the complete elimination of migraines altogether. That lead to lower medical costs and less sick days.


Of course , no surgery is without risk. First of all, you are not guaranteed to experience any relief from migraines at all. Also, common side effects include discomfort at surgical site, temple hollowing, neck weakness, localized hair loss, and eyelid sagging. As with most surgeries, there is the rare possibility that you will not respond well to anesthesia, which can lead to death (though that is very rare). Other rare side effects include phlebitis leading to deep vein thrombosis or pulmonary embolus (blood clot in the lungs).

In Summary

If you’re continuing to suffer from migraines without reprieve, or you just don’t want to have to take pills every day, do your research about newer migraine surgeries. Though they’re not right for everyone, only your doctor and you can make that decision.


I obtain migraines very frequently, especially when I’m on my time period. I’m on birth control currently. I’ve noticed that my migraine headaches have been getting worse — lasting longer, more intense — in recent months. What works for you?
modify: I’ve had migraines since i was about 8, but they do get more frequent with birth control. I have talked to my gyno and tried different delivery controls, and I have spoken to an MD and attempted both daily medication plus ones you take whenever feel a migraine arriving. They just seem to be obtaining worse.

There are losts of good answers, but the best answer:

solution by Newo
I know someone that will push their forehead against the table for a few minutes — to have the pain be concentrated elsewhere.

I think being hydrated and trying to avoid noisy sounds and screamo songs tends to help. As much as I love some heavy metal and shouting (not saying screamo will be heavy), I get some poor headaches after listening for extended periods. Try to bring the refillable water bottle (ofcourse not the typical kind – such as NalGene) to work or college, wherever you go.

You could try rubbing the back of your neck — like 3-4 inches over where your neck fulfills your shoulders. Also, I think that will somehow cardio exercise helps. No idea why, but I have in no way had a headache while or even after a good workout.

additional: Do you get “enough” rest each night? It’s 12: forty eight AM here, and I can guarantee that I get headaches after a week of missing 2 hours a night of rest. (If 8 is the minimal, I get five or even six a night).

Add your own solution in the comments!